2.1 THE RELATIVE IMPORTANCE OF CENTRAL AND BRACHIAL BLOOD PRESSURE IN PREDICTING CARDIOVASCULAR EVENTS: AN INDIVIDUAL PARTICIPANT META-ANALYSIS OF PROSPECTIVE OBSERVATIONAL DATA FROM 22,433 SUBJECTS

Systolic blood pressure (SBP) differs between the brachial artery and aorta.Prospective data suggest that central pressure English Girth predicts future cardiovascular events, but it is unclear if it is superior to brachial pressure.Methods and Results: A systematic review and individual participant data meta-analysis from 15 studies was undertaken

Robotic-assisted laparoscopic radical prostatectomy (RARP) needs a steep Trendelenburg position and a relatively high CO2 insufflation pressure, and patients undergoing RARP are usually elderly.These factors make intraoperative ventilatory care difficult and increase the risk of perioperative pulmonary complications.The aim was to determine the eff

Neudesin (also known as neuron derived neurotrophic factor, Nenf) is a scarcely studied putative non-canonical neurotrophic factor.In order to understand its function in the brain, we performed an extensive behavioral characterization (motor, emotional and cognitive dimensions) of neudesin-null mice.The absence of neudesin leads to an anxious-like

Lipid-lowering therapy is an important tool for the treatment of lipid metabolic diseases, which are increasing in prevalence.However, the failure of conventional lipid-lowering drugs to achieve the desired efficacy in some patients, and the side-effects of these drug regimens, highlight the urgent need for novel lipid-lowering drugs.The liver and

The viscoelastic behaviour of styrene-butadiene-styrene copolymer Motor Coupling modified asphalt binders during tensile test and inverse creep test (retarded strain recovery after unloading) has been analysed in the presented paper.Laboratory tests have been conducted on two specimens of road bitumen: 20/30 and 50/70 penetration grade, which have